Increased B and T Cell Responses in M. bovis Bacille Calmette-Guérin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis Antigen

The only tuberculosis vaccine currently available, bacille Calmette-Guérin (BCG) is a poor inducer of CD8(+) T cells, which are particularly important for the control of latent tuberculosis and protection against reactivation. As the induction of strong CD8(+) T cell responses is a hallmark of DNA v...

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Detalles Bibliográficos
Autores principales: Bruffaerts, Nicolas, Pedersen, Lasse E., Vandermeulen, Gaëlle, Préat, Véronique, Stockhofe-Zurwieden, Norbert, Huygen, Kris, Romano, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501720/
https://www.ncbi.nlm.nih.gov/pubmed/26172261
http://dx.doi.org/10.1371/journal.pone.0132288

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