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N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin

The gene product of SPINT 2, that encodes a transmembrane, Kunitz-type serine protease inhibitor independently designated as HAI-2 or placenta bikunin (PB), is involved in regulation of sodium absorption in human gastrointestinal track. Here, we show that SPINT 2 is expressed as two species of diffe...

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Detalles Bibliográficos
Autores principales: Lai, Ying-Jung J., Chang, Hsiang-Hua D., Lai, Hongyu, Xu, Yuan, Shiao, Frank, Huang, Nanxi, Li, Linpei, Lee, Ming-Shyue, Johnson, Michael D., Wang, Jehng-Kang, Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501743/
https://www.ncbi.nlm.nih.gov/pubmed/26171609
http://dx.doi.org/10.1371/journal.pone.0132163

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