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The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl(−) channel that governs the quantity and composition of epithelial secretions. CFTR function is normally tightly controlled as dysregulation can lead to life-threatening diseases such as secretory diarrhoea and cystic fibrosis. C...

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Detalles Bibliográficos
Autores principales:	Broadbent, Steven D., Ramjeesingh, Mohabir, Bear, Christine E., Argent, Barry E., Linsdell, Paul, Gray, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Ion Channels, Receptors and Transporters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502298/ https://www.ncbi.nlm.nih.gov/pubmed/25277268 http://dx.doi.org/10.1007/s00424-014-1618-8

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