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High Potency of a Novel Resveratrol Derivative, 3,3′,4,4′-Tetrahydroxy-trans-stilbene, against Ovarian Cancer Is Associated with an Oxidative Stress-Mediated Imbalance between DNA Damage Accumulation and Repair

We explored the effect of a new resveratrol (RVT) derivative, 3,3′,4,4′-tetrahydroxy-trans-stilbene (3,3′,4,4′-THS), on viability, apoptosis, proliferation, and senescence of three representative lines of ovarian cancer cells, that is, A2780, OVCAR-3, and SKOV-3, in vitro. In addition, the mechanist...

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Detalles Bibliográficos
Autores principales:	Mikuła-Pietrasik, Justyna, Sosińska, Patrycja, Murias, Marek, Wierzchowski, Marcin, Brewińska-Olchowik, Marta, Piwocka, Katarzyna, Szpurek, Dariusz, Książek, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502315/ https://www.ncbi.nlm.nih.gov/pubmed/26229578 http://dx.doi.org/10.1155/2015/135691

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