Cargando…

Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe

Effective boundary mechanisms halt the spread of repressive histone methylation. In the fission yeast Schizosacchromyces pombe, two factors/elements required for boundary function have been described, the jmjC protein Epe1 and binding sites for the RNA polymerase III transcription factor TFIIIC. Per...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garcia, Jennifer F., Al-Sady, Bassem, Madhani, Hiten D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502379/ https://www.ncbi.nlm.nih.gov/pubmed/25957277 http://dx.doi.org/10.1534/g3.115.018663

Ejemplares similares

Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction
por: Greenstein, R. A., et al.
Publicado: (2022)

Regulation of the heterochromatin spreading reaction by trans-acting factors
por: Hamali, Bulut, et al.
Publicado: (2023)

Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability
por: Greenstein, R A, et al.
Publicado: (2018)

Violence Unchecked by Social Distancing
por: Cannon, Jeremy W., et al.
Publicado: (2020)

Defining the consequences of endogenous genetic variation within a novel family of Schizosaccharomyces pombe heterochromatin nucleating sequences
por: Joshi, Arati, et al.
Publicado: (2021)

A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading
por: Challal, Drice, et al.
Publicado: (2023)

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization
por: Murton, Heather E., et al.
Publicado: (2016)

A Genetic Screen to Discover Pathways Affecting Cohesin Function in Schizosaccharomyces pombe Identifies Chromatin Effectors
por: Chen, Zhiming, et al.
Publicado: (2012)

Reputation‐Sourced Authority and the Prospect of Unchecked Bureaucratic Power
por: Bertelli, Anthony M., et al.
Publicado: (2020)

The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary
por: Tsunemine, Satoru, et al.
Publicado: (2022)

Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly
por: Parsa, Jahan-Yar, et al.
Publicado: (2018)

Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics
por: Al-Sady, Bassem, et al.
Publicado: (2016)

The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states
por: Murawska, Magdalena, et al.
Publicado: (2021)

Phase separation of Dri1 contributes to heterochromatin formation in Schizosaccharomyces pombe
por: Ban, Hyoju, et al.
Publicado: (2022)

A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism
por: Marina, Diana B., et al.
Publicado: (2013)

Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex
por: Cleard, Fabienne, et al.
Publicado: (2017)

Unchecked nick ligation can promote localized genome re-replication
por: Johansson, Erik, et al.
Publicado: (2021)

Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
por: Mizuguchi, Takeshi, et al.
Publicado: (2014)

Subtelomeric Chromatin in the Fission Yeast S. pombe
por: Yadav, Rajesh K., et al.
Publicado: (2021)

Nonredundant Requirement for Multiple Histone Modifications for the Early Anaphase Release of the Mitotic Exit Regulator Cdc14 from Nucleolar Chromatin
por: Hwang, William W., et al.
Publicado: (2009)

Dependency of Heterochromatin Domains on Replication Factors
por: Jahn, Leonie Johanna, et al.
Publicado: (2017)

Centromeric Barrier Disruption Leads to Mitotic Defects in Schizosaccharomyces pombe
por: Gaither, Terilyn L., et al.
Publicado: (2014)

Impact of 1,6-hexanediol on Schizosaccharomyces pombe genome stability
por: Jones, Chance E, et al.
Publicado: (2023)

Genome-Wide Identification of Chromatin Transitional Regions Reveals Diverse Mechanisms Defining the Boundary of Facultative Heterochromatin
por: Li, Guangyao, et al.
Publicado: (2013)

A protocol for transposon insertion sequencing in Schizosaccharomyces pombe to identify factors that maintain heterochromatin
por: Li, Feng, et al.
Publicado: (2021)

Tissue-specific chromatin-binding patterns of Caenorhabditis elegans heterochromatin proteins HPL-1 and HPL-2 reveal differential roles in the regulation of gene expression
por: de la Cruz-Ruiz, Patricia, et al.
Publicado: (2023)

Unchecked immunity: a unique case of sequential immune-related adverse events with Pembrolizumab
por: Shah, N., et al.
Publicado: (2019)

THU478 Unchecked Kinase Activation Underlies Pituitary Adenomas Causing Cushing’s Disease
por: Asuzu, David, et al.
Publicado: (2023)

Cushing's syndrome in children: An unchecked consequence of steroid use by quacks in rural areas of Pakistan
por: Abidi, Syed M Aqeel
Publicado: (2023)

Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation
por: Nugent, Rebecca L, et al.
Publicado: (2010)

Essential Domains of Schizosaccharomyces pombe Rad8 Required for DNA Damage Response
por: Ding, Lin, et al.
Publicado: (2014)

Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4(+)
por: Ranatunga, Nimna S., et al.
Publicado: (2016)

Implementation of dCas9-mediated CRISPRi in the fission yeast Schizosaccharomyces pombe
por: Ishikawa, Ken, et al.
Publicado: (2021)

Post cardiac surgery junctional ectopic tachycardia: A ‘Hit and Run’ tachyarrhythmia as yet unchecked
por: Tharakan, Jaganmohan A, et al.
Publicado: (2014)

Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen
por: Blyth, Julie, et al.
Publicado: (2018)

Preventing Photomorbidity in Long-Term Multi-color Fluorescence Imaging of Saccharomyces cerevisiae and S. pombe
por: Schmidt, Gregor W., et al.
Publicado: (2020)

Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary
por: Benner, Leif, et al.
Publicado: (2019)

Genome-wide screening of genes associated with momilactone B sensitivity in the fission yeast Schizosaccharomyces pombe
por: Tomita, Keisuke, et al.
Publicado: (2021)

Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin
por: Morrison, Olivia, et al.
Publicado: (2021)

Histone H2B Ubiquitination Promotes the Function of the Anaphase-Promoting Complex/Cyclosome in Schizosaccharomyces pombe
por: Elmore, Zachary C., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dn1uipcvr5cb88u8otr2o4fngq