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Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe

Effective boundary mechanisms halt the spread of repressive histone methylation. In the fission yeast Schizosacchromyces pombe, two factors/elements required for boundary function have been described, the jmjC protein Epe1 and binding sites for the RNA polymerase III transcription factor TFIIIC. Per...

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Detalles Bibliográficos
Autores principales:	Garcia, Jennifer F., Al-Sady, Bassem, Madhani, Hiten D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502379/ https://www.ncbi.nlm.nih.gov/pubmed/25957277 http://dx.doi.org/10.1534/g3.115.018663

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