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No Significant Increase in the Δ4- and Δ7-Dafachronic Acid Concentration in the Long-Lived glp-1 Mutant, nor in the Mutants Defective in Dauer Formation

The steroid hormone dafachronic acid (DA) regulates dauer formation and lifespan in Caenorhabditis elegans by binding to the nuclear receptor DAF-12. However, little is known about how DA concentrations change under various physiologic conditions and about how DA/DAF-12 signaling interacts with othe...

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Detalles Bibliográficos
Autores principales:	Li, Tie-Mei, Liu, Weilong, Lu, Shan, Zhang, Yan-Ping, Jia, Le-Mei, Chen, Jie, Li, Xiangke, Lei, Xiaoguang, Dong, Meng-Qiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502381/ https://www.ncbi.nlm.nih.gov/pubmed/25971936 http://dx.doi.org/10.1534/g3.115.018812

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