Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research

The Clustered Regularly Interspaced Short Palindromic Repeat/CRISPR associated (CRISPR/Cas) technology allows rapid, site-specific genome modification in a wide variety of organisms . Proof-of-principle studies in Drosophila melanogaster have used various CRISPR/Cas tools and experimental designs, l...

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Detalles Bibliográficos
Autores principales: Port, Fillip, Muschalik, Nadine, Bullock, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502383/
https://www.ncbi.nlm.nih.gov/pubmed/25999583
http://dx.doi.org/10.1534/g3.115.019083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502383/
https://www.ncbi.nlm.nih.gov/pubmed/25999583
http://dx.doi.org/10.1534/g3.115.019083

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