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Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts

BACKGROUND: Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine and elevated in the regions of tissue injury and inflammatory diseases. The deleterious effects of TNF-α on fibroblasts may aggravate heart inflammation mediated through the up-regulation of adhesion molecules such as vascular...

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Detalles Bibliográficos
Autores principales:	Lin, Chih-Chung, Pan, Chih-Shuo, Wang, Chen-Yu, Liu, Shiau-Wen, Hsiao, Li-Der, Yang, Chuen-Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502472/ https://www.ncbi.nlm.nih.gov/pubmed/26173590 http://dx.doi.org/10.1186/s12929-015-0165-8

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