Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade

Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. ‘Immunotherapy’ is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent...

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Detalles Bibliográficos
Autores principales: Goel, Gaurav, Sun, Weijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502562/
https://www.ncbi.nlm.nih.gov/pubmed/26174086
http://dx.doi.org/10.1186/s13045-015-0185-6
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author Goel, Gaurav
Sun, Weijing
author_facet Goel, Gaurav
Sun, Weijing
author_sort Goel, Gaurav
collection PubMed
description Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. ‘Immunotherapy’ is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies.
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spelling pubmed-45025622015-07-16 Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade Goel, Gaurav Sun, Weijing J Hematol Oncol Review Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. ‘Immunotherapy’ is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies. BioMed Central 2015-07-16 /pmc/articles/PMC4502562/ /pubmed/26174086 http://dx.doi.org/10.1186/s13045-015-0185-6 Text en © Goel and Sun. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Goel, Gaurav
Sun, Weijing
Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title_full Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title_fullStr Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title_full_unstemmed Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title_short Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
title_sort advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502562/
https://www.ncbi.nlm.nih.gov/pubmed/26174086
http://dx.doi.org/10.1186/s13045-015-0185-6
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