Prostate-specific RNA aptamer: promising nucleic acid antibody-like cancer detection

We described the selection of a novel nucleic acid antibody-like prostate cancer (PCa) that specifically binds to the single-stranded DNA molecule from a 277-nt fragment that may have been partially paired and bound to the PCA3 RNA conformational structure. PCA3-277 aptamer ligands were obtained, an...

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Detalles Bibliográficos
Autores principales: Marangoni, Karina, Neves, Adriana F., Rocha, Rafael M., Faria, Paulo R., Alves, Patrícia T., Souza, Aline G., Fujimura, Patrícia T., Santos, Fabiana A. A., Araújo, Thaise G., Ward, Laura S., Goulart, Luiz R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502603/
https://www.ncbi.nlm.nih.gov/pubmed/26174796
http://dx.doi.org/10.1038/srep12090

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