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Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors

Recombinant adeno-associated viruses (rAAV) are promising candidates for gene therapy approaches. The last two decades were particularly fruitful in terms of processes applied in the production and purification of this type of gene transfer vectors. This rapid technological evolution led to better y...

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Detalles Bibliográficos
Autores principales:	Dias Florencio, Gabriella, Precigout, Guillaume, Beley, Cyriaque, Buclez, Pierre-Olivier, Garcia, Luis, Benchaouir, Rachid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502676/ https://www.ncbi.nlm.nih.gov/pubmed/26207258 http://dx.doi.org/10.1038/mtm.2015.24

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