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Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion

MYO1C, a single-headed class I myosin, associates with cholesterol-enriched lipid rafts and facilitates their recycling from intracellular compartments to the cell surface. Absence of functional MYO1C disturbs the cellular distribution of lipid rafts, causes the accumulation of cholesterol-enriched...

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Detalles Bibliográficos
Autores principales: Brandstaetter, Hemma, Kishi-Itakura, Chieko, Tumbarello, David A, Manstein, Dietmar J, Buss, Folma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502697/
https://www.ncbi.nlm.nih.gov/pubmed/25551774
http://dx.doi.org/10.4161/15548627.2014.984272