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Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion
MYO1C, a single-headed class I myosin, associates with cholesterol-enriched lipid rafts and facilitates their recycling from intracellular compartments to the cell surface. Absence of functional MYO1C disturbs the cellular distribution of lipid rafts, causes the accumulation of cholesterol-enriched...
Autores principales: | Brandstaetter, Hemma, Kishi-Itakura, Chieko, Tumbarello, David A, Manstein, Dietmar J, Buss, Folma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502697/ https://www.ncbi.nlm.nih.gov/pubmed/25551774 http://dx.doi.org/10.4161/15548627.2014.984272 |
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