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Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway

Autophagy is an essential component of host innate and adaptive immunity. Viruses have developed diverse strategies for evading or utilizing autophagy for survival. The response of the autophagy pathways to virus invasion is poorly documented. Here, we report on the induction of autophagy initiated...

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Detalles Bibliográficos
Autores principales: Hu, Boli, Zhang, Yina, Jia, Lu, Wu, Huansheng, Fan, Chengfei, Sun, Yanting, Ye, Chengjin, Liao, Min, Zhou, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502722/
https://www.ncbi.nlm.nih.gov/pubmed/25714412
http://dx.doi.org/10.1080/15548627.2015.1017184