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HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)
The hypoxia inducible transcription factor HIF1 activates autophagy, a general catabolic pathway involved in the maintenance of cellular homeostasis. Dysfunction in both autophagy and HIF1 has been implicated in an increasing number of human diseases, including inflammatory bowel disease (IBD), such...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502747/ https://www.ncbi.nlm.nih.gov/pubmed/25484075 http://dx.doi.org/10.4161/15548627.2014.984275 |