Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

BACKGROUND: Myostatin is a protein synthesized and secreted by skeletal muscle that negatively regulates muscle mass. The extent to which circulating myostatin levels change in the context of aging is controversial, largely due to methodological barriers. METHODS: We developed a specific and sensiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergen, H. Robert, Farr, Joshua N., Vanderboom, Patrick M., Atkinson, Elizabeth J., White, Thomas A., Singh, Ravinder J., Khosla, Sundeep, LeBrasseur, Nathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502935/
https://www.ncbi.nlm.nih.gov/pubmed/26180626
http://dx.doi.org/10.1186/s13395-015-0047-5

Ejemplares similares

Ejemplares similares