Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase**

The ceramides are a family of bioactive lipid-derived messengers involved in the control of cellular senescence, inflammation, and apoptosis. Ceramide hydrolysis by acid ceramidase (AC) stops the biological activity of these substances and influences survival and function of normal and neoplastic ce...

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Detalles Bibliográficos
Autores principales: Pizzirani, Daniela, Bach, Anders, Realini, Natalia, Armirotti, Andrea, Mengatto, Luisa, Bauer, Inga, Girotto, Stefania, Pagliuca, Chiara, De Vivo, Marco, Summa, Maria, Ribeiro, Alison, Piomelli, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502975/
https://www.ncbi.nlm.nih.gov/pubmed/25395373
http://dx.doi.org/10.1002/anie.201409042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502975/
https://www.ncbi.nlm.nih.gov/pubmed/25395373
http://dx.doi.org/10.1002/anie.201409042

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