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Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine
There is a major need for new adjuvants to improve the efficacy of seasonal and pandemic influenza vaccines. Advax is a novel polysaccharide adjuvant based on delta inulin that has been shown to enhance the immunogenicity of influenza vaccine in animal models and human clinical trials. To better und...
Autores principales: | Li, Lei, Honda-Okubo, Yoshikazu, Li, Connie, Sajkov, Dimitar, Petrovsky, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503308/ https://www.ncbi.nlm.nih.gov/pubmed/26177480 http://dx.doi.org/10.1371/journal.pone.0132003 |
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