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Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections, which comprise nearly 8% of the human genome(1). The most recently acquired human ERV is HERV-K (HML-2), which repeatedly infected the primate lineage both before and after the divergence of humans and chimpanzees(2,3). Un...

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Detalles Bibliográficos
Autores principales: Grow, Edward J., Flynn, Ryan A., Chavez, Shawn L., Bayless, Nicholas L., Wossidlo, Mark, Wesche, Daniel, Martin, Lance, Ware, Carol, Blish, Catherine A., Chang, Howard Y., Reijo Pera, Renee A., Wysocka, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503379/
https://www.ncbi.nlm.nih.gov/pubmed/25896322
http://dx.doi.org/10.1038/nature14308