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Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients

The HOXB13 germline variant G84E (rs138213197) was recently described in men of European descent, with the highest prevalence in Northern Europe. The G84E mutation has not been found in patients of African or Asian ancestry, which may carry other HOXB13 variants, indicating allelic heterogeneity dep...

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Detalles Bibliográficos
Autores principales: Maia, Sofia, Cardoso, Marta, Pinto, Pedro, Pinheiro, Manuela, Santos, Catarina, Peixoto, Ana, Bento, Maria José, Oliveira, Jorge, Henrique, Rui, Jerónimo, Carmen, Teixeira, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503425/
https://www.ncbi.nlm.nih.gov/pubmed/26176944
http://dx.doi.org/10.1371/journal.pone.0132728