A Proline-Rich Domain in the Genotype 4 Hepatitis E Virus ORF3 C-Terminus Is Crucial for Downstream V(105)DLP(108) Immunoactivity

The hepatitis E virus (HEV) is responsible for serious viral hepatitis worldwide. Animals are considered a reservoir of HEV, particularly pigs. While HEV infection in pigs and dogs is always asymptomatic, the virus causes high death rates in patients with pre-existing chronic liver disease and pregn...

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Detalles Bibliográficos
Autores principales: Wang, Heng, Ji, Fangxiao, Liang, Huanbin, Gu, Honglang, Ning, Zhangyong, Liu, Rongchang, Zhang, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503470/
https://www.ncbi.nlm.nih.gov/pubmed/26177202
http://dx.doi.org/10.1371/journal.pone.0133282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503470/
https://www.ncbi.nlm.nih.gov/pubmed/26177202
http://dx.doi.org/10.1371/journal.pone.0133282

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