Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress

Two insults often underlie a variety of eye diseases including glaucoma, optic atrophy, and retinal degeneration—defects in mitochondrial function and aberrant Rhodopsin trafficking. Although mitochondrial defects are often associated with oxidative stress, they have not been linked to Rhodopsin tra...

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Detalles Bibliográficos
Autores principales: Jaiswal, Manish, Haelterman, Nele A., Sandoval, Hector, Xiong, Bo, Donti, Taraka, Kalsotra, Auinash, Yamamoto, Shinya, Cooper, Thomas A., Graham, Brett H., Bellen, Hugo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503542/
https://www.ncbi.nlm.nih.gov/pubmed/26176594
http://dx.doi.org/10.1371/journal.pbio.1002197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503542/
https://www.ncbi.nlm.nih.gov/pubmed/26176594
http://dx.doi.org/10.1371/journal.pbio.1002197

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