Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal

The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated a...

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Autores principales: Miguel, Maria Graça, Gago, Custódia, Antunes, Maria Dulce, Megías, Cristina, Cortés-Giraldo, Isabel, Vioque, Javier, Lima, A. Sofia, Figueiredo, A. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503548/
https://www.ncbi.nlm.nih.gov/pubmed/26229547
http://dx.doi.org/10.1155/2015/851721
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author Miguel, Maria Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, A. Sofia
Figueiredo, A. Cristina
author_facet Miguel, Maria Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, A. Sofia
Figueiredo, A. Cristina
author_sort Miguel, Maria Graça
collection PubMed
description The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(•+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
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spelling pubmed-45035482015-07-30 Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal Miguel, Maria Graça Gago, Custódia Antunes, Maria Dulce Megías, Cristina Cortés-Giraldo, Isabel Vioque, Javier Lima, A. Sofia Figueiredo, A. Cristina Evid Based Complement Alternat Med Research Article The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(•+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells. Hindawi Publishing Corporation 2015 2015-07-02 /pmc/articles/PMC4503548/ /pubmed/26229547 http://dx.doi.org/10.1155/2015/851721 Text en Copyright © 2015 Maria Graça Miguel et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Miguel, Maria Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, A. Sofia
Figueiredo, A. Cristina
Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_full Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_fullStr Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_full_unstemmed Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_short Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_sort antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in portugal
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503548/
https://www.ncbi.nlm.nih.gov/pubmed/26229547
http://dx.doi.org/10.1155/2015/851721
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