Emergence, Retention and Selection: A Trilogy of Origination for Functional De Novo Proteins from Ancestral LncRNAs in Primates

While some human-specific protein-coding genes have been proposed to originate from ancestral lncRNAs, the transition process remains poorly understood. Here we identified 64 hominoid-specific de novo genes and report a mechanism for the origination of functional de novo proteins from ancestral lncR...

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Detalles Bibliográficos
Autores principales: Chen, Jia-Yu, Shen, Qing Sunny, Zhou, Wei-Zhen, Peng, Jiguang, He, Bin Z., Li, Yumei, Liu, Chu-Jun, Luan, Xuke, Ding, Wanqiu, Li, Shuxian, Chen, Chunyan, Tan, Bertrand Chin-Ming, Zhang, Yong E., He, Aibin, Li, Chuan-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503675/
https://www.ncbi.nlm.nih.gov/pubmed/26177073
http://dx.doi.org/10.1371/journal.pgen.1005391

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