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Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2

Synapsins are pre-synaptic vesicle-associated proteins linked to the pathogenesis of epilepsy through genetic association studies in humans. Deletion of synapsins causes an excitatory/inhibitory imbalance, exemplified by the epileptic phenotype of synapsin knockout mice. These mice develop handling-...

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Detalles Bibliográficos
Autores principales: Chugh, Deepti, Ali, Idrish, Bakochi, Anahita, Bahonjic, Elma, Etholm, Lars, Ekdahl, Christine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503715/
https://www.ncbi.nlm.nih.gov/pubmed/26177381
http://dx.doi.org/10.1371/journal.pone.0132366