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Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2
Synapsins are pre-synaptic vesicle-associated proteins linked to the pathogenesis of epilepsy through genetic association studies in humans. Deletion of synapsins causes an excitatory/inhibitory imbalance, exemplified by the epileptic phenotype of synapsin knockout mice. These mice develop handling-...
Autores principales: | Chugh, Deepti, Ali, Idrish, Bakochi, Anahita, Bahonjic, Elma, Etholm, Lars, Ekdahl, Christine T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503715/ https://www.ncbi.nlm.nih.gov/pubmed/26177381 http://dx.doi.org/10.1371/journal.pone.0132366 |
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