Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays

Phenotypic assays have a proven track record for generating leads that become first-in-class therapies. Whole cell assays that inform on a phenotype or mechanism also possess great potential in drug repositioning studies by illuminating new activities for the existing pharmacopeia. The National Cent...

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Detalles Bibliográficos
Autores principales: Lee, Jonathan A., Shinn, Paul, Jaken, Susan, Oliver, Sarah, Willard, Francis S., Heidler, Steven, Peery, Robert B., Oler, Jennifer, Chu, Shaoyou, Southall, Noel, Dexheimer, Thomas S., Smallwood, Jeffrey, Huang, Ruili, Guha, Rajarshi, Jadhav, Ajit, Cox, Karen, Austin, Christopher P., Simeonov, Anton, Sittampalam, G. Sitta, Husain, Saba, Franklin, Natalie, Wild, David J., Yang, Jeremy J., Sutherland, Jeffrey J., Thomas, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503722/
https://www.ncbi.nlm.nih.gov/pubmed/26177200
http://dx.doi.org/10.1371/journal.pone.0130796

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