Cargando…

Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia

Cytogenetically normal acute myeloid leukemia (CN-AML) patients harboring RUNX1 mutations have a dismal prognosis with anthracycline/cytarabine-based chemotherapy. We aimed to develop an in vivo model of RUNX1-mutated, CN-AML in which the nature of residual disease in this molecular disease subset c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sivagnanalingam, Umayal, Balys, Marlene, Eberhardt, Allison, Wang, Nancy, Myers, Jason R., Ashton, John M., Becker, Michael W., Calvi, Laura M., Mendler, Jason H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503761/ https://www.ncbi.nlm.nih.gov/pubmed/26177509 http://dx.doi.org/10.1371/journal.pone.0132375

Ejemplares similares

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia
por: Fu, Lin, et al.
Publicado: (2016)

RUNX1 mutation and elevated FLT3 gene expression cooperates to induce inferior prognosis in cytogenetically normal acute myeloid leukemia patients
por: Rehman, Atia, et al.
Publicado: (2021)

Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia
por: Niederwieser, Christian, et al.
Publicado: (2014)

Molecular Mutations and Their Cooccurrences in Cytogenetically Normal Acute Myeloid Leukemia
por: Wang, Mengning, et al.
Publicado: (2017)

Monitoring Minimal Residual Disease in RUNX1-Mutated Acute Myeloid Leukemia
por: Nachmias, Boaz, et al.
Publicado: (2022)

Increased expression of RUNX3 inhibits normal human myeloid development
por: Menezes, Ana Catarina, et al.
Publicado: (2022)

BAALC expression: a suitable marker for prognostic risk stratification and detection of residual disease in cytogenetically normal acute myeloid leukemia
por: Weber, S, et al.
Publicado: (2014)

DNA sequencing of a cytogenetically normal acute myeloid leukemia genome
por: Ley, Timothy J, et al.
Publicado: (2008)

Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics
por: Gregory, Tara K, et al.
Publicado: (2009)

Prognostic role of ACTL10 in Cytogenetic Normal Acute Myeloid Leukemia
por: Lai, Rui, et al.
Publicado: (2020)

Redefining prognostication of de novo cytogenetically normal acute myeloid leukemia in young adults
por: Tsui, Sze P., et al.
Publicado: (2020)

The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia
por: Cao, Ling, et al.
Publicado: (2019)

The Importance of Targeted Next-Generation Sequencing Usage in Cytogenetically Normal Myeloid Malignancies
por: Atli, Emine Ikbal, et al.
Publicado: (2021)

Serial cytogenetic studies of human colonic tumour xenografts.
por: Reeves, B. R., et al.
Publicado: (1978)

Acute promyelocytic leukemia relapsing into acute myeloid leukemia-M2 with normal cytogenetics
por: Sahoo, Ranjit Kumar, et al.
Publicado: (2013)

Wilms Tumor 1 Gene Mutations in Patients with Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2014)

High NCALD expression predicts poor prognosis of cytogenetic normal acute myeloid leukemia
por: Song, Ying, et al.
Publicado: (2019)

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics
por: Fernandez-Mercado, Marta, et al.
Publicado: (2012)

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients
por: Bou Samra, Elias, et al.
Publicado: (2012)

Prognostic Prediction of Cytogenetically Normal Acute Myeloid Leukemia Based on a Gene Expression Model
por: Yang, Liu, et al.
Publicado: (2021)

Overexpression of Prohibitin 2 Protein is Associated with Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia
por: Lee, Young Eun, et al.
Publicado: (2022)

RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner
por: Abdallah, Mohamed Gaber, et al.
Publicado: (2021)

Cytogenetics’ impact on the prognosis of acute myeloid leukemia
por: Gupta, Monika, et al.
Publicado: (2019)

Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia
por: Shi, Jin-long, et al.
Publicado: (2015)

KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia
por: Zhou, Jing-Dong, et al.
Publicado: (2017)

Evaluation of BAALC gene expression in normal cytogenetic acute myeloid leukemia patients in north-east of Iran
por: Amirpour, Mojgan, et al.
Publicado: (2016)

Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement
por: Tokunaga, Kenji, et al.
Publicado: (2017)

Elucidation of Novel Therapeutic Targets for Acute Myeloid Leukemias with RUNX1-RUNX1T1 Fusion
por: Yun, Jae Won, et al.
Publicado: (2019)

Volunteer unrelated donor cell‐derived acute myeloid leukemia with RUNX1‐RUNX1T1
por: Hagiwara, Shinya, et al.
Publicado: (2021)

Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia
por: Klco, Jeffery, et al.
Publicado: (2023)

High expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia
por: Fu, Lin, et al.
Publicado: (2016)

MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia
por: Ma, Qiu-Ling, et al.
Publicado: (2018)

Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia
por: Yan, Han, et al.
Publicado: (2016)

A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia
por: Zhu, Ruiqi, et al.
Publicado: (2017)

Prognostic value of CD25/CD123 pattern of expression in acute myeloid leukemia patients with normal cytogenetic
por: Aref, Salah, et al.
Publicado: (2020)

Aberrant Chloride Intracellular Channel 4 Expression Is Associated With Adverse Outcome in Cytogenetically Normal Acute Myeloid Leukemia
por: Huang, Sai, et al.
Publicado: (2020)

Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia
por: Mat Yusoff, Yuslina, et al.
Publicado: (2021)

Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia
por: Papaioannou, Dimitrios, et al.
Publicado: (2021)

Clinical Implication of DNMT3A and TET2 Genes Mutations in Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2022)

Altered expression of imprinted genes in patients with cytogenetically normal‑acute myeloid leukemia: Implications for leukemogenesis and survival outcomes
por: Yang, Ming-Yu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5psan7lbbm495vjfia5c76u2ac