Gastrointestinal pH and Transit Time Profiling in Healthy Volunteers Using the IntelliCap System Confirms Ileo-Colonic Release of ColoPulse Tablets

INTRODUCTION: ColoPulse tablets are an innovative development in the field of oral dosage forms characterized by a distal ileum and colon-specific release. Previous studies in humans showed release in the ileo-colonic region, but the relationship between gastrointestinal pH and release was not exper...

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Detalles Bibliográficos
Autores principales: Maurer, Jacoba M., Schellekens, Reinout C. A., van Rieke, Hèlen M., Wanke, Christoph, Iordanov, Ventzeslav, Stellaard, Frans, Wutzke, Klaus D., Dijkstra, Gerard, van der Zee, Margot, Woerdenbag, Herman J., Frijlink, Henderik W., Kosterink, Jos G. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503763/
https://www.ncbi.nlm.nih.gov/pubmed/26177019
http://dx.doi.org/10.1371/journal.pone.0129076

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