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Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation

Chronic graft-versus-host disease (cGvHD) is the major source of late phase morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Humanized acute GvHD (aGvHD) in vivo models using NOD-SCID il2rγ-/- (NSG) mice are well described and are important tools for investigating pa...

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Detalles Bibliográficos
Autores principales: Fujii, Hisaki, Luo, Zhi-Juan, Kim, Hye Jin, Newbigging, Susan, Gassas, Adam, Keating, Armand, Egeler, R. Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503770/
https://www.ncbi.nlm.nih.gov/pubmed/26176698
http://dx.doi.org/10.1371/journal.pone.0133216

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