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Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation
Chronic graft-versus-host disease (cGvHD) is the major source of late phase morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Humanized acute GvHD (aGvHD) in vivo models using NOD-SCID il2rγ-/- (NSG) mice are well described and are important tools for investigating pa...
Autores principales: | Fujii, Hisaki, Luo, Zhi-Juan, Kim, Hye Jin, Newbigging, Susan, Gassas, Adam, Keating, Armand, Egeler, R. Maarten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503770/ https://www.ncbi.nlm.nih.gov/pubmed/26176698 http://dx.doi.org/10.1371/journal.pone.0133216 |
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