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Artificial MiRNA Knockdown of Platelet Glycoprotein lbα: A Tool for Platelet Gene Silencing

In recent years, candidate genes and proteins implicated in platelet function have been identified by various genomic approaches. To elucidate their exact role, we aimed to develop a method to apply miRNA interference in platelet progenitor cells by using GPIbα as a proof-of-concept target protein....

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Detalles Bibliográficos
Autores principales: Thijs, Tim, Broos, Katleen, Soenen, Stefaan J., Vandenbulcke, Aline, Vanhoorelbeke, Karen, Deckmyn, Hans, Salles-Crawley, Isabelle I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503784/
https://www.ncbi.nlm.nih.gov/pubmed/26176854
http://dx.doi.org/10.1371/journal.pone.0132899