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Artificial MiRNA Knockdown of Platelet Glycoprotein lbα: A Tool for Platelet Gene Silencing
In recent years, candidate genes and proteins implicated in platelet function have been identified by various genomic approaches. To elucidate their exact role, we aimed to develop a method to apply miRNA interference in platelet progenitor cells by using GPIbα as a proof-of-concept target protein....
Autores principales: | Thijs, Tim, Broos, Katleen, Soenen, Stefaan J., Vandenbulcke, Aline, Vanhoorelbeke, Karen, Deckmyn, Hans, Salles-Crawley, Isabelle I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503784/ https://www.ncbi.nlm.nih.gov/pubmed/26176854 http://dx.doi.org/10.1371/journal.pone.0132899 |
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