Cargando…
Diagnosis, investigation and management of hereditary spastic paraplegias in the era of next-generation sequencing
The hereditary spastic paraplegias (HSPs) are a group of genetic conditions in which spastic paralysis of the legs is the principal clinical feature. This is caused by a relatively selective distal axonal degeneration involving the longest axons of the corticospinal tracts. Consequently, these condi...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503825/ https://www.ncbi.nlm.nih.gov/pubmed/25480570 http://dx.doi.org/10.1007/s00415-014-7598-y |