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EGCG reverses human neutrophil elastase-induced migration in A549 cells by directly binding to HNE and by regulating α1-AT
Lung carcinogenesis is a complex process that occurs in unregulated inflammatory environment. EGCG has been extensively investigated as a multi-targeting anti-tumor and anti-inflammatory compound. In this study, we demonstrated a novel mechanism by which EGCG reverses the neutrophil elastase-induced...
Autores principales: | Xiaokaiti, Yilixiati, Wu, Haoming, Chen, Ya, Yang, Haopeng, Duan, Jianhui, Li, Xin, Pan, Yan, Tie, Lu, Zhang, Liangren, Li, Xuejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503950/ https://www.ncbi.nlm.nih.gov/pubmed/26177797 http://dx.doi.org/10.1038/srep11494 |
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