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Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation

This article reports an efficient CH activation process for regioselective halogenation of 1,4-benzodiazepinones. Direct halogenation with NXS (X = Br, I) affords halogenated benzodiazepinones on the central aromatic ring whereas catalyst (Pd(OAc)(2)) controlled CH activation furnishes regioselectiv...

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Detalles Bibliográficos
Autores principales:	Abdelkafi, Hajer, Cintrat, Jean-Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503988/ https://www.ncbi.nlm.nih.gov/pubmed/26179245 http://dx.doi.org/10.1038/srep12131

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