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P2X(7)R activation drives distinct IL-1 responses in dendritic cells compared to macrophages

The P2X(7)R is a functionally distinct member of the P2X family of non-selective cation channels associated with rapid activation of the inflammasome complex and signalling interleukin (IL)-1β release in macrophages. The main focus of this investigation was to compare P2X(7)R-driven IL-1 production...

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Detalles Bibliográficos
Autores principales:	Englezou, Pavlos C., Rothwell, Simon W., Ainscough, Joseph S., Brough, David, Landsiedel, Robert, Verkhratsky, Alexei, Kimber, Ian, Dearman, Rebecca J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504032/ https://www.ncbi.nlm.nih.gov/pubmed/26068648 http://dx.doi.org/10.1016/j.cyto.2015.05.013

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