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Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

INTRODUCTION: Interleukin (IL)-21 is a key cytokine in autoimmune diseases such as systemic lupus erythematosus (SLE) by its regulation of autoantibody production and inflammatory responses. The objective of this study is to investigate the signaling capacity of IL-21 in T and B cells and assess its...

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Detalles Bibliográficos
Autores principales:	Rasmussen, Tue Kruse, Andersen, Thomas, Bak, Rasmus Otkjær, Yiu, Gloria, Sørensen, Christian Møller, Stengaard-Pedersen, Kristian, Mikkelsen, Jacob Giehm, Utz, Paul Joseph, Holm, Christian Kanstrup, Deleuran, Bent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504038/ https://www.ncbi.nlm.nih.gov/pubmed/26055806 http://dx.doi.org/10.1186/s13075-015-0660-z

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