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Anticancer Effect of a Novel Proteasome Inhibitor, YSY01A, via G2/M Arrest in PC-3M Cells in vitro and in vivo

YSY01A is a new tripeptideboronic acid and an analog of PS341. However, YSY01A's antitumor effects and mechanism have not yet been elucidated. This study demonstrates that YSY01A inhibited proteasome activity by combining with the chymotrypsin-like (CT-L) site (β5i/β5), the post-glutamyl peptid...

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Detalles Bibliográficos
Autores principales:	Zhang, Mei, Yuan, Xia, Xu, Bo, Guo, Wei, Ran, Fu-Xiang, Li, Run-Tao, Cui, Jing-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504105/ https://www.ncbi.nlm.nih.gov/pubmed/26185531 http://dx.doi.org/10.7150/jca.11785

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