Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

BACKGROUND: Type 2 diabetes is associated with abnormal electrical conduction and sudden cardiac death, but the pathogenic mechanism remains unknown. This study describes electrophysiological alterations in a diet-induced pre-diabetic rat model and examines the underlying mechanism. METHODS: Sprague...

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Detalles Bibliográficos
Autores principales: Axelsen, Lene Nygaard, Calloe, Kirstine, Braunstein, Thomas Hartig, Riemann, Mads, Hofgaard, Johannes Pauli, Liang, Bo, Jensen, Christa Funch, Olsen, Kristine Boisen, Bartels, Emil D., Baandrup, Ulrik, Jespersen, Thomas, Nielsen, Lars Bo, Holstein-Rathlou, Niels-Henrik, Nielsen, Morten Schak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504126/
https://www.ncbi.nlm.nih.gov/pubmed/26169175
http://dx.doi.org/10.1186/s12933-015-0246-8

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