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DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites
Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction sites, modern virtual screening tools developed for optimal performance agains...
Autores principales: | Gowthaman, Ragul, Lyskov, Sergey, Karanicolas, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504481/ https://www.ncbi.nlm.nih.gov/pubmed/26181386 http://dx.doi.org/10.1371/journal.pone.0131612 |
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