Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria

FoxP3+ regulatory CD4 T cells (T(regs)) help to maintain the delicate balance between pathogen-specific immunity and immune-mediated pathology. Prior studies suggest that T(regs) are induced by P. falciparum both in vivo and in vitro; however, the factors influencing T(reg) homeostasis during acute...

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Detalles Bibliográficos
Autores principales: Boyle, Michelle J., Jagannathan, Prasanna, Farrington, Lila A., Eccles-James, Ijeoma, Wamala, Samuel, McIntyre, Tara I, Vance, Hilary M., Bowen, Katherine, Nankya, Felistas, Auma, Ann, Nalubega, Mayimuna, Sikyomu, Esther, Naluwu, Kate, Rek, John, Katureebe, Agaba, Bigira, Victor, Kapisi, James, Tappero, Jordan, Muhindo, Mary K, Greenhouse, Bryan, Arinaitwe, Emmanuel, Dorsey, Grant, Kamya, Moses R., Feeney, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504515/
https://www.ncbi.nlm.nih.gov/pubmed/26182204
http://dx.doi.org/10.1371/journal.ppat.1005041

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