Aging and Autophagic Function Influences the Progressive Decline of Adult Drosophila Behaviors

Multiple neurological disorders are characterized by the abnormal accumulation of protein aggregates and the progressive impairment of complex behaviors. Our Drosophila studies demonstrate that middle-aged wild-type flies (WT, ~4-weeks) exhibit a marked accumulation of neural aggregates that is comm...

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Detalles Bibliográficos
Autores principales: Ratliff, Eric P., Mauntz, Ruth E., Kotzebue, Roxanne W., Gonzalez, Arysa, Achal, Madhulika, Barekat, Ayeh, Finley, Kaelyn A., Sparhawk, Jonathan M., Robinson, James E., Herr, Deron R., Harris, Greg L., Joiner, William J., Finley, Kim D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504520/
https://www.ncbi.nlm.nih.gov/pubmed/26182057
http://dx.doi.org/10.1371/journal.pone.0132768

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