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Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report

Anti-N-methyl-D-aspartate receptor (anti-MMDAR) encephalitis is an immune-mediated encephalitis mainly affecting young women. We describe the case of a 21-year-old woman who developed a classical form of anti-NMDAR encephalitis during the 10th week of gestation. The patient had been treated with met...

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Autores principales: Mathis, Stéphane, Pin, Jean-Christophe, Pierre, Fabrice, Ciron, Jonathan, Iljicsov, Anna, Lamy, Matthias, Neau, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504573/
https://www.ncbi.nlm.nih.gov/pubmed/26131809
http://dx.doi.org/10.1097/MD.0000000000001034
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author Mathis, Stéphane
Pin, Jean-Christophe
Pierre, Fabrice
Ciron, Jonathan
Iljicsov, Anna
Lamy, Matthias
Neau, Jean-Philippe
author_facet Mathis, Stéphane
Pin, Jean-Christophe
Pierre, Fabrice
Ciron, Jonathan
Iljicsov, Anna
Lamy, Matthias
Neau, Jean-Philippe
author_sort Mathis, Stéphane
collection PubMed
description Anti-N-methyl-D-aspartate receptor (anti-MMDAR) encephalitis is an immune-mediated encephalitis mainly affecting young women. We describe the case of a 21-year-old woman who developed a classical form of anti-NMDAR encephalitis during the 10th week of gestation. The patient had been treated with methylpredinsolone and intravenous immunoglobulins. Birth history of the child was normal, with normal APGAR score. The clinical symptoms of the patient have improved after a few months. This rare occurrence during pregnancy (only 9 other cases described) presents an opportunity to highlight the importance of making the earliest possible diagnosis of this treatable and potentially reversible encephalitis, and to educate gynecologists, psychiatrists, anesthetists, and neurologists on this potential cause of psychiatric and neurological manifestations during pregnancy.
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spelling pubmed-45045732015-08-05 Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report Mathis, Stéphane Pin, Jean-Christophe Pierre, Fabrice Ciron, Jonathan Iljicsov, Anna Lamy, Matthias Neau, Jean-Philippe Medicine (Baltimore) 5300 Anti-N-methyl-D-aspartate receptor (anti-MMDAR) encephalitis is an immune-mediated encephalitis mainly affecting young women. We describe the case of a 21-year-old woman who developed a classical form of anti-NMDAR encephalitis during the 10th week of gestation. The patient had been treated with methylpredinsolone and intravenous immunoglobulins. Birth history of the child was normal, with normal APGAR score. The clinical symptoms of the patient have improved after a few months. This rare occurrence during pregnancy (only 9 other cases described) presents an opportunity to highlight the importance of making the earliest possible diagnosis of this treatable and potentially reversible encephalitis, and to educate gynecologists, psychiatrists, anesthetists, and neurologists on this potential cause of psychiatric and neurological manifestations during pregnancy. Wolters Kluwer Health 2015-07-02 /pmc/articles/PMC4504573/ /pubmed/26131809 http://dx.doi.org/10.1097/MD.0000000000001034 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 5300
Mathis, Stéphane
Pin, Jean-Christophe
Pierre, Fabrice
Ciron, Jonathan
Iljicsov, Anna
Lamy, Matthias
Neau, Jean-Philippe
Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title_full Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title_fullStr Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title_full_unstemmed Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title_short Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report
title_sort anti-nmda receptor encephalitis during pregnancy: a case report
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504573/
https://www.ncbi.nlm.nih.gov/pubmed/26131809
http://dx.doi.org/10.1097/MD.0000000000001034
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