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Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study
Patients who need both capsule endoscopy (CE) and colonoscopy often undergo both examinations on the same day to avoid repeated bowel preparation and fasting. Sedation can relieve pain and is commonly used for colonoscopies but may influence the CE completion rate. To determine whether sedation with...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504626/ https://www.ncbi.nlm.nih.gov/pubmed/26166122 http://dx.doi.org/10.1097/MD.0000000000001140 |
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author | Gan, Huo-Ye Weng, Yi-Jie Qiao, Wei-Guang Chen, Zhen-Yu Xu, Zhi-Min Bai, Yang Gong, Wei Wan, Tian-Mo Pan, De-Shou Shi, Yong-Sheng Qiu, Ai-Jun Zhi, Fa-Chao |
author_facet | Gan, Huo-Ye Weng, Yi-Jie Qiao, Wei-Guang Chen, Zhen-Yu Xu, Zhi-Min Bai, Yang Gong, Wei Wan, Tian-Mo Pan, De-Shou Shi, Yong-Sheng Qiu, Ai-Jun Zhi, Fa-Chao |
author_sort | Gan, Huo-Ye |
collection | PubMed |
description | Patients who need both capsule endoscopy (CE) and colonoscopy often undergo both examinations on the same day to avoid repeated bowel preparation and fasting. Sedation can relieve pain and is commonly used for colonoscopies but may influence the CE completion rate. To determine whether sedation with propofol influences the completion rate and small-bowel transit time (SBTT) of CE. From July 2014 to December 2014, patients (18–65 years old) who needed both CE and colonoscopy were assessed consecutively for enrollment in our study. Colonoscopies were performed with or without sedation based on patient preferences on the day of capsule ingestion. The completion rate, SBTT, and diagnostic yield of CEs were recorded. Patients’ satisfaction and pain scores were also recorded. Sedation with propofol had no significant effect on CE completion rates (83.3% sedation group vs 81.8% nonsedation group, P = 0.86) but was associated with increased SBTT (403.6 ± 160.3 sedation group vs 334.5 ± 134.4 nonsedation group, P = 0.006). The diagnostic yields in the sedation and nonsedation groups were 69.4% and 65.9%, respectively (P = 0.74). The median satisfaction scores were 8.6 in the sedation group and 3.5 in the nonsedation group (P < 0.001). Median pain scores were 1.4 in the sedation group and 6.7 in the nonsedation group (P < 0.001). Sedation with propofol increased SBTT but had no effect on CE completion rates, suggesting that CE and colonoscopy with propofol can be performed on the same day (clinical trial registration number: ChiCTR-ONRC-14004866). |
format | Online Article Text |
id | pubmed-4504626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-45046262015-08-05 Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study Gan, Huo-Ye Weng, Yi-Jie Qiao, Wei-Guang Chen, Zhen-Yu Xu, Zhi-Min Bai, Yang Gong, Wei Wan, Tian-Mo Pan, De-Shou Shi, Yong-Sheng Qiu, Ai-Jun Zhi, Fa-Chao Medicine (Baltimore) 4500 Patients who need both capsule endoscopy (CE) and colonoscopy often undergo both examinations on the same day to avoid repeated bowel preparation and fasting. Sedation can relieve pain and is commonly used for colonoscopies but may influence the CE completion rate. To determine whether sedation with propofol influences the completion rate and small-bowel transit time (SBTT) of CE. From July 2014 to December 2014, patients (18–65 years old) who needed both CE and colonoscopy were assessed consecutively for enrollment in our study. Colonoscopies were performed with or without sedation based on patient preferences on the day of capsule ingestion. The completion rate, SBTT, and diagnostic yield of CEs were recorded. Patients’ satisfaction and pain scores were also recorded. Sedation with propofol had no significant effect on CE completion rates (83.3% sedation group vs 81.8% nonsedation group, P = 0.86) but was associated with increased SBTT (403.6 ± 160.3 sedation group vs 334.5 ± 134.4 nonsedation group, P = 0.006). The diagnostic yields in the sedation and nonsedation groups were 69.4% and 65.9%, respectively (P = 0.74). The median satisfaction scores were 8.6 in the sedation group and 3.5 in the nonsedation group (P < 0.001). Median pain scores were 1.4 in the sedation group and 6.7 in the nonsedation group (P < 0.001). Sedation with propofol increased SBTT but had no effect on CE completion rates, suggesting that CE and colonoscopy with propofol can be performed on the same day (clinical trial registration number: ChiCTR-ONRC-14004866). Wolters Kluwer Health 2015-07-13 /pmc/articles/PMC4504626/ /pubmed/26166122 http://dx.doi.org/10.1097/MD.0000000000001140 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 4500 Gan, Huo-Ye Weng, Yi-Jie Qiao, Wei-Guang Chen, Zhen-Yu Xu, Zhi-Min Bai, Yang Gong, Wei Wan, Tian-Mo Pan, De-Shou Shi, Yong-Sheng Qiu, Ai-Jun Zhi, Fa-Chao Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title | Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title_full | Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title_fullStr | Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title_full_unstemmed | Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title_short | Sedation With Propofol Has No Effect on Capsule Endoscopy Completion Rates: A Prospective Single-Center Study |
title_sort | sedation with propofol has no effect on capsule endoscopy completion rates: a prospective single-center study |
topic | 4500 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504626/ https://www.ncbi.nlm.nih.gov/pubmed/26166122 http://dx.doi.org/10.1097/MD.0000000000001140 |
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