Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions

Lactate has long been considered a “waste” by-product of cell metabolism, and it accumulates at sites of inflammation. Recent findings have identified lactate as an active metabolite in cell signalling, although its effects on immune cells during inflammation are largely unexplored. Here we ask whet...

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Detalles Bibliográficos
Autores principales: Haas, Robert, Smith, Joanne, Rocher-Ros, Vidalba, Nadkarni, Suchita, Montero-Melendez, Trinidad, D’Acquisto, Fulvio, Bland, Elliot J., Bombardieri, Michele, Pitzalis, Costantino, Perretti, Mauro, Marelli-Berg, Federica M., Mauro, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504715/
https://www.ncbi.nlm.nih.gov/pubmed/26181372
http://dx.doi.org/10.1371/journal.pbio.1002202

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