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A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA

The protein antizyme is a negative regulator of cellular polyamine concentrations from yeast to mammals. Synthesis of functional antizyme requires programmed +1 ribosomal frameshifting at the 3′ end of the first of two partially overlapping ORFs. The frameshift is the sensor and effector in an autor...

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Detalles Bibliográficos
Autores principales:	Yordanova, Martina M., Wu, Cheng, Andreev, Dmitry E., Sachs, Matthew S., Atkins, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Protein Synthesis and Degradation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505036/ https://www.ncbi.nlm.nih.gov/pubmed/25998126 http://dx.doi.org/10.1074/jbc.M115.647065

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