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Spontaneous Transformation of Murine Oviductal Epithelial Cells: A Model System to Investigate the Onset of Fallopian-Derived Tumors

High-grade serous carcinoma (HGSC) is the most lethal ovarian cancer histotype. The fallopian tube secretory epithelial cells (FTSECs) are a proposed progenitor cell type. Genetically altered FTSECs form tumors in mice; however, a spontaneous HGSC model has not been described. Apart from a subpopula...

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Detalles Bibliográficos
Autores principales:	Endsley, Michael P., Moyle-Heyrman, Georgette, Karthikeyan, Subbulakshmi, Lantvit, Daniel D., Davis, David A., Wei, Jian-Jun, Burdette, Joanna E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505108/ https://www.ncbi.nlm.nih.gov/pubmed/26236688 http://dx.doi.org/10.3389/fonc.2015.00154

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