De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis

The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated gen...

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Detalles Bibliográficos
Autores principales: Gupta, Anil Kumar, Srivastava, Saumya, Singh, Amit, Singh, Sarman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Eukaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505137/
https://www.ncbi.nlm.nih.gov/pubmed/26184949
http://dx.doi.org/10.1128/genomeA.00809-15
Descripción
Sumario:The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated genes of the whole genome of the PKDL strain.

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