De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis

The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated gen...

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Detalles Bibliográficos
Autores principales: Gupta, Anil Kumar, Srivastava, Saumya, Singh, Amit, Singh, Sarman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Eukaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505137/
https://www.ncbi.nlm.nih.gov/pubmed/26184949
http://dx.doi.org/10.1128/genomeA.00809-15
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author Gupta, Anil Kumar
Srivastava, Saumya
Singh, Amit
Singh, Sarman
author_facet Gupta, Anil Kumar
Srivastava, Saumya
Singh, Amit
Singh, Sarman
author_sort Gupta, Anil Kumar
collection PubMed
description The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated genes of the whole genome of the PKDL strain.
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spelling pubmed-45051372015-07-29 De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis Gupta, Anil Kumar Srivastava, Saumya Singh, Amit Singh, Sarman Genome Announc Eukaryotes The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated genes of the whole genome of the PKDL strain. American Society for Microbiology 2015-07-16 /pmc/articles/PMC4505137/ /pubmed/26184949 http://dx.doi.org/10.1128/genomeA.00809-15 Text en Copyright © 2015 Gupta et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Eukaryotes
Gupta, Anil Kumar
Srivastava, Saumya
Singh, Amit
Singh, Sarman
De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title_full De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title_fullStr De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title_full_unstemmed De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title_short De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis
title_sort de novo whole-genome sequence and annotation of a leishmania strain isolated from a case of post-kala-azar dermal leishmaniasis
topic Eukaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505137/
https://www.ncbi.nlm.nih.gov/pubmed/26184949
http://dx.doi.org/10.1128/genomeA.00809-15
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