Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis

We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM). Various spiro-polyquinane derivatives have been assembled via RCM as a key step.

Detalles Bibliográficos
Autores principales: Kotha, Sambasivarao, Chinnam, Ajay Kumar, Ali, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505178/
https://www.ncbi.nlm.nih.gov/pubmed/26199668
http://dx.doi.org/10.3762/bjoc.11.126
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author Kotha, Sambasivarao
Chinnam, Ajay Kumar
Ali, Rashid
author_facet Kotha, Sambasivarao
Chinnam, Ajay Kumar
Ali, Rashid
author_sort Kotha, Sambasivarao
collection PubMed
description We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM). Various spiro-polyquinane derivatives have been assembled via RCM as a key step.
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spelling pubmed-45051782015-07-21 Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis Kotha, Sambasivarao Chinnam, Ajay Kumar Ali, Rashid Beilstein J Org Chem Full Research Paper We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM). Various spiro-polyquinane derivatives have been assembled via RCM as a key step. Beilstein-Institut 2015-07-06 /pmc/articles/PMC4505178/ /pubmed/26199668 http://dx.doi.org/10.3762/bjoc.11.126 Text en Copyright © 2015, Kotha et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Kotha, Sambasivarao
Chinnam, Ajay Kumar
Ali, Rashid
Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title_full Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title_fullStr Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title_full_unstemmed Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title_short Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
title_sort hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505178/
https://www.ncbi.nlm.nih.gov/pubmed/26199668
http://dx.doi.org/10.3762/bjoc.11.126
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AT alirashid hybridmacrocycleformationandspiroannulationoncissyncistricyclo630026undeca311dioneanditscongenersviaringclosingmetathesis

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